"Memory-stealing protein" reveals Alzheimer's disease 34 years ago

"Memory-stealing protein" reveals Alzheimer's disease 34 years ago

NEW YORK [Reuters Health] – Early warning signs of Alzheimer's disease can be detected decades before the onset of symptoms, according to a new study.

The study found that at-risk patients had more Tau protein in their spinal fluid up to 34 years before they showed signs of amnesia.

Tau protein is intertwined in brain regions important to memory, yet it has not been shown to cause Alzheimer's disease.

The new study showed that the accumulation of toxic protein passes through the vital organ, one of the symptoms of "memory theft" disorder.

The study was conducted by Johns Hopkins University, led by Dr. Laurent Younis, Professor and Head of Applied Mathematics and Statistics.

"Our study suggests that it may be possible to use EEG and spinal fluid analysis to assess the risk of Alzheimer's disease before the onset of the most common symptoms, such as moderate cognitive impairment," Dr. Yunus said.

The researchers said earlier evidence suggests that the mechanisms behind the onset of Alzheimer's disease could begin more than a decade before the onset of cognitive impairment.

This has made experts question whether it is possible to test the vital signs of dementia in the "pre-clinical" stage of the disease.

To do this, the researchers analyzed the medical records of 290 people over the age of 40 or older, all of whom were "normally normal" at the beginning of the study, while most had a family history with Alzheimer's disease that increased their risk of developing the disease.

The researchers collected spinal cord samples from all participants every two years between 1995 and 2005, and examined the samples using magnetic resonance imaging [MRI] technology.

Patients were also tested for memory, learning, reading and attention annually, from 1995 to 2013.

Over the years, researchers have tracked any clinical changes associated with Alzheimer's disease and the time it took for symptoms to appear.

Results showed that 209 participants remained "cognitively normal" while the remaining 81 participants were diagnosed with mild cognitive impairment or Alzheimer's disease.

In the 81 patients with Alzheimer's, scientists identified slight changes in the results of their cognitive tests from 11 to 15 years before they experienced cognitive impairment.

The results also revealed increases in the rate of change in the Tao protein in their vertebral fluid about 34.4 years before the onset of cognitive decline.

There were changes in the brain tests of patients between two and eight years before the onset of symptoms.

However, researchers confirm that brain changes vary greatly among people and only relatively few participants are adopted.

Even if vital markers of Alzheimer's disease are identified, there is no drug that can prevent or slow down the disease, the researchers say.

However, researchers hope that one day the study will lead to a test that determines the risk of Alzheimer's disease in the individual to help doctors choose the best treatment, which focuses on reducing symptoms.

Source: Daily Mail


Nawfal Mohammed

Hello I am a student at law college and I am still studying i'M GOOG IN : Blogging, MMA fighter, Designer, Website Management, Bodybuilding, etc BUT my Hobbies :Learn languages, horseback riding, motorcycles and more

Leave a Reply

Your email address will not be published. Required fields are marked *

Related Articles

Back to top button

Adblock Detected

Please consider supporting us by disabling your ad blocker